As originally posted in the ֱ Gazette

Queen’s researchers receive funding from the Canadian Institutes of Health Research for projects addressing human health issues from cancer to pain and healthy aging.

Queen’s researchers have been successful in garnering over $11.5 million in funding from the Canadian Institutes of Health Research (CIHR) Project Grant competition, a program designed to capture and support ideas with the greatest potential to advance health-related knowledge in Canada. As CIHR’s largest funding program, the Project Grant competitions support multi-year grants for researchers at various stages in their career.

The funding is divided among 13 Queen’s research projects (10 fully funded and three $100,000 priority announcement grants) that contributed to a success rate of 26.3 per cent compared to 15 per cent nationally. Of the funded projects, half are led by early-career researchers and two applications ranked first in their panels.

“I am continually impressed by the success our researchers see in increasingly competitive funding environments such as the CIHR Project Grants,” says Kimberly Woodhouse, Vice-Principal (Research). “This funding will help our researchers advance innovation in research designed to better understand human health and to benefit Canadians.”

The funded projects include:

Principal Investigator Project Title Funding Awarded

 (Biomedical and Molecular Sciences; Queen’s Cancer Research Institute)

Elucidating the Role Extracellular Vesicles play in leukaemogenesis $1,071,000
 (Pathology and Molecular Medicine; Canadian Cancer Trials Group) Immunophenotyping Malignant Pleural Mesothelioma: Identifying Predictive and Prognostic Biomarkers for Combinatorial Immunotherapy

$872,865

 (Emergency Medicine) PEITHO-3. Reduced-dose Thrombolytic Treatment for Patients with Higher-intermediate Risk Acute Pulmonary Embolism $478,125
and  (Rehabilitation Therapy; Health Services and Policy Research Institute) Fostering Healthy Aging in Naturally Occurring Retirement Communities: A Mixed Methods Explanatory Case Study $1,583,288 
 (Biomedical and Molecular Sciences; Centre for Neuroscience Studies) Investigating the Role of Cognitive Brain Networks in Human Motor Learning

$734,400

 (Anesthesiology & Perioperative Medicine) The PRECISE trial – Pain Relief Combination Intervention StratEgies $100,000
 (Family Medicine) and  (Anesthesiology & Perioperative Medicine) Development of a Validated Method to Identify Patients with Chronic Pain in Electronic Medical Records and Administrative Health Data to Advance Clinical Research and Patient Care $673,200 
 (Medicine; Canadian Cancer Trials Group) Randomized Phase 3 Evaluation of Lower Dose (3-2-1 Strategy) vs. Full Dose of Ibrutinib for the Treatment of Chronic Lymphocytic Leukemia $100,000
 (Medicine; Translational Institute of Medicine) Intraplaque Composition Combined with Stress Echo for Cardiac Risk Stratification $918,000
 (Kinesiology and Health Studies) It takes an island: local and sustainable child health and well-being promotion in Antigua and Barbuda $100,000
 (Oncology; Canadian Cancer Trials Group) SPECT-CT Guided ELEctive Contralateral Neck Treatment (SELECT) for Patients with Lateralized Oropharyngeal Cancer: A Phase III Randomized Controlled Trial

$3,203,435

 (Pathology and Molecular Medicine) Dysregulation of TET2 and DNMT3A Promotes Pulmonary Arterial Hypertension (PAH) through Inflammation: A New Mechanism of PAH $891,225
 (Biomedical and Molecular Sciences) Investigating the Role of Endocannabinoids in Endometriosis Pathophysiology and Determine Efficacy of Cannabinoids as a Novel Therapeutic Modality $868,275

For more details, including project summaries, visit the Government of Canada’s .