Sinclair Cancer Research Institute (SCRI)

Paul Kubes

kvd1 — Thu, 14 Dec 2023 15:09:57 +0000

Deciphering complex immune pathways

Immune cells allow the human body to exist in a stable chemical and physical state (homeostasis) and have the ability to adapt as we develop and age. But changes to immune cell biology, for example, from chronic perturbations, alter homeostasis, leading to disease. To understand how and why these changes occur to our stable state, we must apply an interdisciplinary approach that combines physiology and immunology and need to decipher the complex immune pathways involved in cancer and chronic disease.

The beauty of Queen's research – photo essay

kvd1 — Wed, 29 Mar 2023 19:49:02 +0000

With a focus on the UN SDGs and advancing social impact, the annual Queen’s Art of Research photo contest highlights six winning entries.

#QueensuResearch | With a focus on the UN SDGs and advancing social impact, the annual Queen's Art of Research photo contest highlights six winning entries.

Advancing Canada’s research infrastructure

kvd1 — Mon, 19 Dec 2022 16:37:36 +0000

On Friday, at SNOLAB, the Honourable François-Philippe Champagne, Minister of Innovation, Science and Industry, recognized the key role of research infrastructure by announcing more than $628 million to support 19 research infrastructure projects at institutions across the country, including two research facilities affiliated with Queen’s University.

Research Funding

Leaders in cancer research

kvd1 — Fri, 04 Feb 2022 20:19:31 +0000

To recognize World Cancer Day, Queen’s is highlighting current partnerships and research projects to develop novel treatments, support better outcomes, and advance quality of life for people with cancer globally.

#QueensuResearch | To recognize World Cancer Day, Queen’s is highlighting current partnerships and research projects to develop novel treatments, support better outcomes, and advance quality of life for people with cancer globally.

Trialled and true

kvd1 — Wed, 17 Nov 2021 14:57:37 +0000

In celebration of the 25^th anniversary of the Canada Foundation for Innovation (CFI), we are profiling one of our CFI Major Science Initiatives, The Canadian Cancer Trials Group.

#QueensuResearch | Clinical trials at Queen’s University help determine life-changing diagnostics, treatments, and prevention methods for cancer.

Clinical trials for game-changing cancer research

MLR7 — Tue, 02 Feb 2021 18:41:48 +0000

From its hub at Queen’s, CCTG conducts wide-ranging clinical trials that lead to better outcomes and quality of life for cancer patients here and around the globe.

#QueensuResearch | From its hub at Queen’s, CCTG conducts wide-ranging clinical trials that lead to better outcomes and quality of life for cancer patients here and around the globe.

Is DNA key to whether you get COVID-19?

kvd1 — Wed, 12 Aug 2020 17:27:27 +0000

The strength and health of one’s immune system is one key indicator of susceptibility to contracting pathogens, including the novel coronavirus. However, new evidence that may suggest more men get coronavirus than women has motivated an international hunt for which genes make people especially vulnerable or resistant to COVID-19.

Confronting COVID-19

Tags:

COVID-19

Coronavirus

DNA

Cancer

Research

Genomes

Critical funding for health research

kvd1 — Wed, 12 Feb 2020 15:42:28 +0000

Seven Queen’s University researchers are contributing their knowledge in the areas of melanoma, intensive care unit survivors, postoperative pain, diabetes medication, Indigenous public health, and depression thanks to funding from the Canadian Institutes of Health Research.

Queen’s received a total of $3.95 million from the Fall 2019 CIHR Project Grant competition, a program that helps advance health-related research. With an eye on collaboration, the competition funds both individuals and groups of researchers at any career stage in all areas of health-related research.

Research Funding

Tags:

One Step Closer to Unravelling Cancer

MLR7 — Tue, 24 Sep 2019 19:23:34 +0000

Before realizing that she had made an important discovery, Caitlin Miron (PhD' 18) thought she had made a mistake.

Before realizing that she had made an important discovery, Caitlin Miron thought she had made a mistake.

Deliberating on dilbit

MLR7 — Tue, 24 Sep 2019 17:18:56 +0000

Short for “diluted bitumen,” the term "dilbit" refers to a chemical concoction that makes petroleum extracted from oil sands easier to transport. Diane Orihel – an assistant professor in the School of Environmental Studies and Queen’s National Scholar – is exploring the effects of this increasingly controversial material.

Diane Orihel is exploring diluted bitumen – an increasingly controversial chemical concoction that makes petroleum extracted from oil sands easier to transport.

Mathieu Crupi: Cancer Research

moonr — Tue, 30 Apr 2019 18:20:17 +0000

In this interview for the Queen’s Alumni Review magazine, cancer researcher Mathieu Crupi discusses his research and talks about why community outreach and fundraising are so important to him.

https://www.youtube.com/watch?v=rizXzxSzVvM

Christopher Booth

moonr — Thu, 14 Mar 2019 13:49:56 +0000

Achieving Better Outcomes for Patients with Cancer

The results of clinical trials give us a sense of what is possible when it comes to new cancer treatments. But, there are many uncertainties around how these new treatments are being used, and how outcomes for patients compare with the results from clinical trials. Dr. Christopher Booth, Canada Research Chair in Population Cancer Care, wants to improve both cancer care and outcomes for Canadians by addressing these questions.

Evolving Clinical Trials through Collaboration

stratg — Thu, 04 Oct 2018 18:35:41 +0000

Dr. Janet Dancey is the Director of the Canadian Cancer Trials Group, also known as the CCTG, and a Professor in the Department of Oncology at Queen’s. She is also the Director of the High Impact Clinical Trials Program at the Ontario Institute for Cancer Research. The CCTG has over 80 member institutions, comprising over 2100 Canadian investigators who have facilitated over 500 trials in more than 40 countries. They are also the only non-American partner of the US National Clinical Trials Network.

Sinclair Cancer Research Institute

stratg — Thu, 04 Oct 2018 14:32:16 +0000

Leaving home

stratg — Tue, 02 Oct 2018 19:58:17 +0000

Eric Y Lian

My focus is cancer cell invasion and migration. This spheroid of cells is embedded in a 3D protein matrix and fluorescently stained for 3 proteins. Individual cells can be seen radiating away on all sides. The cells use integrin (red) and actin (green) to pull on the protein matrix and move, while cadherin (blue), binds and holds cells together within the spheroid. Cadherin normally holds clumps of cells together and allows them to form structures such as tissues and organs. This picture shows how invading cells lose their cadherin and express large amounts of integrin and actin, and it demonstrates some of the protein expression changes that cancer cells undergo which allow them to invade away from a tumour.

Location of photograph:

A microscope slide

Prize name:

Shortlisted image

Submission Year:

2015-16